The call is to leave a certain social situation, move into your own loneliness and find the jewel, the center that’s impossible to find when you’re socially engaged. You are thrown off center, and when you feel off-center, it’s time to go. This is the departure when the hero feels something has been lost and goes to find it. You are to cross the threshold into a new life. It’s a dangerous adventure, because you are moving out of the sphere of the knowledge of you and your community.
Joseph Campbell, Reflections on the Art of Living – A Joseph Campbell Companion